Clinical Evaluation of Roche SD Biosensor Rapid Antigen Test for SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged >1 year ago but still keeps a strong grip not only on daily life but also on diagnostic capacities. Reverse transcription PCR (RT-PCR) has been the standard for diagnosis of acute infection but has several limitations, such as the requirement for specialized laboratory infrastructure, trained personnel, and reagents that have been in shortage globally .In addition, the current turnaround time from sample collection to reporting of the result may take >48 hours (J. van Beek et al., unpub. data,compromising effectiveness of triage, isolation, and contact tracing strategies. Rapid antigen detection tests (Ag RDT) for SARS-CoV-2 appeared on the market in early 2020, but initial reports of poor performance and the lack of independent evaluation results made governments reluctant to invest and consider inclusion into testing algorithms.As of February 2021, more than 140 assays are on the market , but relatively few have been extensively validated V.M. Corman et al., unpub. data.Initial results show that these tests are suitable for detecting early-onset cases with high viral load.
As expected, the sensitivity of the tests is lower than that of RT-PCR, but in patients in the early phase of illness who have high viral load, performance meets World Health Organization–set criteria of >80% sensitivity and >97% specificity compared with nucleic acid detection methods . Thus, these tests could be useful in identifying the most infectious persons (J. van Beek et al.). In an outbreak scenario, diagnostics with lower sensitivity but a faster result can render interventions more effective than standard tests . Implementation of Ag RDT into testing algorithms would enable rapid detection and isolation of new cases Roche rapid antigen test sensitivity and thereby support the test, trace, and isolate strategy with the intent to stop transmission chains and reduce the impact of coronavirus disease (COVID-19).
In this study, we assessed the performance of the Roche SD Biosensor SARS-CoV-2 rapid antigen test compared with both RT-PCR and virus culture.
- We conducted the field evaluation study at a large public health service testing facility in Rotterdam-Rijnmond, the Netherlands, where most visitors sought care for COVID-19 symptoms.
- Every person >18 years of age who had an appointment for SARS-CoV-2 RT-PCR testing was invited to participate. An additional nasopharyngeal swab specimen was obtained for the Ag RDT in parallel and processed onsite to compare sensitivity and specificity to RT-PCR.
- All samples positive by Ag RDT and PCR were cultured to correlate results with infectivity. The medical research ethics committee of Utrecht decided the study was not subject to the Medical Research Involving Human Subjects Act and did not require full review by an accredited committee (protocol no. 20-606/C).
Testing Population, Setup and Patient Recruitment
The study was conducted at the largest drive-through testing location in Rotterdam-Rijnmond, at which testing is by appointment only. Eligibility for a free-of-charge test included either presence of symptoms or close contact with a confirmed SARS-CoV-2–infected person. Most persons who requested testing had symptoms. At the entrance of the testing site, we approached all persons >18 years of age; after providing written informed consent, they were enrolled in the study and directed to one of the dedicated testing posts for sampling.
Enrolled persons were also asked to fill in a clinical questionnaire stating the reason for appointment, date of onset or end date of symptoms, and a list of symptoms (fever, sore throat, coughing, shortness of breath/tightness, runny nose, diarrhea, eye complaints, nausea, rash, chills, headache, pain when breathing, coughing phlegm, muscle pain, painful/swollen lymph nodes, fatigue, vomiting, joint pain, loss of appetite, nosebleed, other). The study was conducted for 5 days to achieve the target of 800–1,000 participants. The SARS-CoV-2 rapid antigen test distributed by Roche SD Biosensor was provided by the Ministry of Health, Welfare, and Sport.
Testing Site Setup and the Mobile Laboratory
From the 6 available testing posts, we designated 2 posts for sample collection from study participant on the basis of 3 factors: maximum number of subjects per test post (≈150/day); known number of appointments per day; and expected enrollment rate based on initial results from other study sites in the Netherlands. We expected to include a maximum of 300 persons/day. The site’s regular trained personnel performed swabbing to avoid variations to the process. Testing was done on benchtop, in a mobile laboratory unit by trained staff dressed in full personal protective equipment (goggles, FFP3 mask, gloves, and disposable gown). Samples for the Ag RDT were collected at regular intervals and processed as soon as possible within 30 mins in convenient batches (5–10 tests at a time). Swab specimens and RDT devices were inactivated in chlorine and disposed of as biohazard material. Results were recorded in a Microsoft Access database designated for this study.
Specimen Collection, Testing and Culture Procedures
Standard method for SARS-CoV-2 testing was by RT-PCR, which was conducted in parallel with the Ag RDT on separate swab specimens. Two swab specimens (1 oropharyngeal and 1 nasopharyngeal swab) were taken for RT-PCR and virus culture, placed directly in 3 mL universal transport media and shipped to the Erasmus MC viroscience diagnostic laboratory (Rotterdam, the Netherlands). For the Ag RDT evaluation, a second nasopharyngeal swab specimen was taken from the same nostril, using the swab included in the kits, to directly compare RT-PCR results with Ag RDT results.
Swabs were placed into empty tubes to transport to the mobile laboratory onsite. Routine RT-PCR testing was performed on combined oropharyngeal and one nasopharyngeal swabs in virus transport medium using the cobas SARS-CoV-2 test on the COBAS6800 (Roche Diagnostics). Because cycle threshold (Ct) values differ between PCR methods, genome copies per milliliter were calculated based on an in-house established standard curve. The leftover virus transport medium from the oropharyngeal and nasopharyngeal swabs was directly inoculated onto Vero cells clone 118 without freezing or extended storage. Samples were cultured for 7 days; once cytopathic effect was visible, the presence of SARS-CoV-2 was confirmed with immunofluorescent detection of SARS CoV-2 nucleocapsid protein.
For the Ag RDT, the SD Biosensor SARS-CoV-2 rapid antigen test distributed by Roche (reference no. 9901-NCOV-01G; lot no. QCO3020079/Sub:A-2) was performed immediately onsite following manufacturer’s instructions. A 4-grade scaling readout (−; +/−, +; ++) representing the strength of the test band was used . Time until positive results was logged as <5 min, <10 min (not part of the manufacturer’s instructions for use), or 15 min; recommended readout was 15–30 min. When results were dubious (i.e., test line barely visible or labeled as +/− but regarded as positive test result), 2 persons performed the readout.
Data Analysis
We merged data from the Ag RDT, RT-PCR, virus culture, and clinical questionnaire using Microsoft Access and data performed analysis using R version 4.0.2 . Sensitivity and specificity of Ag RDT were calculated in relation to the RT-PCR results. Wilcoxon score interval was used to determine CIs of proportions.
Rapid detection of infection is essential for stopping the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The Roche SD Biosensor rapid antigen test for SARS-CoV-2 was evaluated in a nonhospitalized symptomatic population. We rapid-tested a sample onsite and compared results with those from reverse transcription PCR and virus culture. We analyzed date of onset and symptoms using data from a clinical questionnaire.
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Accu-Tell COVID-19 IgG/IgM Rapid Test |
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2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma) |
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GEN-402-25tests | All test | 25 tests | 292.8 EUR |
Panbio™ COVID-19 Ag Rapid Test Device (Nasal) |
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41FK11 | Abbott | 25 Tests/Kit | 128 EUR |
H.pylori Antigen Rapid Test |
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NOVATest Antigen Rapid Test Kit (For Single Use) (NOVA Test) |
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Giardia (GIA) Antigen Test Card |
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Rabies Virus Antigen Test Card |
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CEA (Cancer antigen) ELISA test |
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COVID-19 Antigen Rapid Test |
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ICOV-802H | Hangzhou AllTest Biotech | 25 Tests | 12.5 EUR |
Canine Pancreatitis Antigen Test Card |
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CA50 (Cancer antigen) ELISA test |
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S. pneumoniae Antigen Rapid Test |
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Salmonella typhi Antigen Rapid Test |
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CDV/CAV Antigen Combo Test Card |
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Canine Parvovirus (CPV) Antigen Test Card |
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Canine Coronavirus (CCV) Antigen Test Card |
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SARS-CoV-2 Antigen Rapid Test |
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Feline Coronavirus (FCoV) Antigen Test Card |
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Canine Parainfluenza Virus Antigen Test Card |
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NOVATest Antigen Rapid Kit (NOVA Test) |
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Feline Herpes Virus (FHV) Antigen Test Card |
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Canine Adenovirus 2 (CAV) Antigen Test Card |
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CDV/CAV/CIV Antigen Combo Test Card |
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Canine Early Pregnancy (RLN) Antigen Test Card |
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SARS-CoV-2 Antigen Rapid Test Kit |
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SARS-CoV-2 Antigen Rapid Test Kit |
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COVID-19 Antigen Rapid Test Pen (Saliva) |
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HBsAg hepatitis B surface antigen ELISA test |
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Healgen Coronavirus Rapid Antigen Test (Professional use) |
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Recombinant human RHD antigen |
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Rapid Response COVID-19 Saliva Rapid Antigen Test |
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BSV-COV-2C25B | BioServUK | 25 tests | Ask for price |
TruStrip RDT Anthrax Protective antigen 83 (PA83) Rapid Test cards, 25/pk |
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800-100-RDT-25 | Alpha Diagnostics | 1 pk | 489.6 EUR |
Rat CA125(Carbohydrate Antigen 125) ELISA Kit |
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Rat Cd44(CD44 antigen) ELISA Kit |
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Mouse CA125(Carbohydrate Antigen 125) ELISA Kit |
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Rat Alcam(CD166 antigen) ELISA Kit |
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Human CD48(CD48 antigen) ELISA Kit |
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Mouse CD44( CD44 antigen) ELISA Kit |
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Human CD44(CD44 antigen) ELISA Kit |
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Human CD81(CD81 antigen) ELISA Kit |
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EH7221 | FN Test | 96T | 681.12 EUR |
Canine Parvovirus Antigen (CPV Ag) Rapid Test Kit |
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HG001 | EnoGene | 10 Tests/Kit | 16.1 EUR |
Recombinant human Lymphocyte antigen 6K |
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Human CD109(CD109 antigen) ELISA Kit |
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Human CD177(CD177 antigen) ELISA Kit |
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Mouse Alcam(CD166 antigen) ELISA Kit |
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Human ALCAM(CD166 antigen) ELISA Kit |
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Human CD276(CD276 antigen) ELISA Kit |
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Canine Coronavirus Antigen (CCV Ag) Rapid Test Kit |
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Feline Herpesvirus Antigen (FHV Ag) Rapid Test Kit |
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Feline Calicivirus Antigen (FCV Ag) Rapid Test Kit |
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Feline Infectious peritonitis virus (FIPV) Antigen Test Card |
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Human CA-125(Carbohydrate Antigen 125) ELISA Kit |
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EH0361 | FN Test | 96T | 571.5 EUR |
Feline Coronavirus Antigen (FCoV Ag) Rapid Test Kit |
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Human MKI67(Antigen KI-67) ELISA Kit |
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Human CD5L(CD5 antigen-like) ELISA Kit |
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Mouse CD5l( CD5 antigen-like) ELISA Kit |
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Human CD52(CAMPATH-1 antigen) ELISA Kit |
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Human CEA(Carcinoembryonic Antigen) ELISA Kit |
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Recombinant human B-lymphocyte antigen CD19 |
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Recombinant human B-lymphocyte antigen CD20 |
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Human LY75(Lymphocyte antigen 75) ELISA Kit |
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Rat PSA(Prostate Specific Antigen) ELISA Kit |
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Rat TPA(Tissue Polypeptide Antigen) ELISA Kit |
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Mouse Ly6c1( Lymphocyte antigen 6C1) ELISA Kit |
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Human CA50(Carbohydrate Antigen 50) ELISA Kit |
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EH1396 | FN Test | 96T | 681.12 EUR |
Mouse PSA(Prostate Specific Antigen) ELISA Kit |
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EM1314 | FN Test | 96T | 628.92 EUR |
Lysis Buffer for SARS-CoV-2 Antigen Test Development |
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LY-14 | ACROBIOSYSTEMS | 10ml | 973.7 EUR |
Recombinant human Melanoma-associated antigen 3 |
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Recombinant human Melanoma-associated antigen 2 |
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Mouse TPA(Tissue Polypeptide Antigen) ELISA Kit |
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EM1633 | FN Test | 96T | 628.92 EUR |
Human TPA(Tissue Polypeptide Antigen) ELISA Kit |
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EH3901 | FN Test | 96T | 628.92 EUR |
Human HLA-A(Leukocyte Antigen A) ELISA Kit |
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Rat Tp53(Cellular tumor antigen p53) ELISA Kit |
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Human GPA33(Cell surface A33 antigen) ELISA Kit |
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EH1535 | FN Test | 96T | 681.12 EUR |
Human PSCA(Prostate stem cell antigen) ELISA Kit |
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EH2380 | FN Test | 96T | 681.12 EUR |
Human SSA(Sjogren syndrome antigen A) ELISA Kit |
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EH4256 | FN Test | 96T | 628.92 EUR |
Human CYFRA21-1(Cytokeratin Fragment Antigen 21-1) ELISA Kit |
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EH0364 | FN Test | 96T | 628.92 EUR |
Human LCA/CD45(Leukocyte Common Antigen) ELISA Kit |
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EH3290 | FN Test | 96T | 628.92 EUR |
Human SPAG5(sperm associated antigen 5) ELISA Kit |
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EH4134 | FN Test | 96T | 628.92 EUR |
Human MS4A1(B-lymphocyte antigen CD20) ELISA Kit |
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EH14877 | FN Test | 96T | 628.92 EUR |
Human Streptococcus Pneumoniae (SP) Antigen Rapid Test Kit |
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abx092096-20tests | Abbexa | 20 tests | 477.6 EUR |
Human CD69(Early activation antigen CD69) ELISA Kit |
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EH1314 | FN Test | 96T | 681.12 EUR |
Human CD2(T-cell surface antigen CD2) ELISA Kit |
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EH0466 | FN Test | 96T | 681.12 EUR |
Human SPAG1(Sperm-associated antigen 1) ELISA Kit |
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EH2525 | FN Test | 96T | 681.12 EUR |
Human fPSA(Free Prostate Specific Antigen) ELISA Kit |
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EH3082 | FN Test | 96T | 628.92 EUR |
Recombinant human T-lymphocyte activation antigen CD80 |
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Rat PCNA(Proliferating Cell Nuclear Antigen) ELISA Kit |
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ER1234 | FN Test | 96T | 628.92 EUR |
Human CD72(B-cell differentiation antigen) ELISA Kit |
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EH4178 | FN Test | 96T | 681.12 EUR |
Human HBeAg(hepatitis B virus E Antigen) ELISA Kit |
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EH4105 | FN Test | 96T | 571.5 EUR |
Human PCNA(Proliferating Cell Nuclear Antigen) ELISA Kit |
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EH3523 | FN Test | 96T | 628.92 EUR |
Mouse Pcna(Proliferating cell nuclear antigen) ELISA Kit |
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EM0416 | FN Test | 96T | 681.12 EUR |
Human MAGEC1(Melanoma-associated antigen C1) ELISA Kit |
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EH1115 | FN Test | 96T | 681.12 EUR |
Human MAGEA3(Melanoma-associated antigen 3) ELISA Kit |
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EH9915 | FN Test | 96T | 681.12 EUR |
Canine Distemper Virus Antigen (CDV Ag) Rapid Test Kit |
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HG002 | EnoGene | 10 Tests/Kit | 16.1 EUR |
Canine Influenza virus Antigen (CIV Ag) Rapid Test Kit |
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HG028 | EnoGene | 10 Tests/Kit | 16.1 EUR |
Feline Leukemia Virus Antigen (FeLv Ag) Rapid Test Kit |
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Human EPCA2(Early Prostate Cancer Antigen 2) ELISA Kit |
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EH1781 | FN Test | 96T | 628.92 EUR |
Mouse CD209a(CD209 antigen-like protein A) ELISA Kit |
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EM0786 | FN Test | 96T | 681.12 EUR |
Human TES(Testin) ELISA Kit |
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EH1738 | FN Test | 96T | 681.12 EUR |
Mouse CD14(Monocyte differentiation antigen CD14) ELISA Kit |
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EM0039 | FN Test | 96T | 681.12 EUR |
Human HbsAg(hepatitis B virus Surface Antigen) ELISA Kit |
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EH4002 | FN Test | 96T | 628.92 EUR |
Avacta AffiDX SARS-CoV-2 Antigen Lateral Flow Test |
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Canine Relaxin Antigen (RLN Ag) Rapid Pregnancy Test Kit |
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HG043 | EnoGene | 10 Tests/Kit | 16.1 EUR |
Human CD80(T-lymphocyte activation antigen CD80) ELISA Kit |
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EH0088 | FN Test | 96T | 681.12 EUR |
Human CD86(T-lymphocyte activation antigen CD86) ELISA Kit |
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EH0659 | FN Test | 96T | 628.92 EUR |
Human proPSA(precursor of Prostate Specific Antigen) ELISA Kit |
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EH3659 | FN Test | 96T | 628.92 EUR |
Human CD34(Hematopoietic progenitor cell antigen CD34) ELISA Kit |
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EH2020 | FN Test | 96T | 681.12 EUR |
Human SLC3A2(4F2 cell-surface antigen heavy chain) ELISA Kit |
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EH2042 | FN Test | 96T | 681.12 EUR |
Feline Panleukopenia Virus Antigen (FPV Ag) Rapid Test Kit |
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HG004 | EnoGene | 10 Tests/Kit | 16.1 EUR |
Human CD58(Lymphocyte function-associated antigen 3) ELISA Kit |
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EH1082 | FN Test | 96T | 628.92 EUR |
Recombinant human Lymphocyte antigen 6 complex locus protein G6d |
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P1817 | FN Test | 100ug | Ask for price |
Human MNDA(Myeloid cell nuclear differentiation antigen) ELISA Kit |
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EH1924 | FN Test | 96T | 681.12 EUR |
Mouse Etaa1(Ewing's tumor-associated antigen 1 homolog) ELISA Kit |
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EM0570 | FN Test | 96T | 681.12 EUR |
Mouse Eapa2(Experimental autoimmune prostatitis antigen 2) ELISA Kit |
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EM0797 | FN Test | 96T | 681.12 EUR |
Human MLANA(Melanoma antigen recognized by T-cells 1) ELISA Kit |
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EH1242 | FN Test | 96T | 681.12 EUR |
T(Testosterone) ELISA Kit |
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EU0400 | FN Test | 96T | 571.5 EUR |
Mouse CTLA4(Cytotoxic T-Lymphocyte Associated Antigen 4) ELISA Kit |
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EM0062 | FN Test | 96T | 628.92 EUR |
Human SDCCAG3(Serologically defined colon cancer antigen 3) ELISA Kit |
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EH1858 | FN Test | 96T | 681.12 EUR |
Human HIV(1+2 antibodies plus p24 antigen (4th Generation) ELISA Kit |
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EH4101 | FN Test | 96T | 571.5 EUR |
Rat T(Testosterone) ELISA Kit |
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ER1462 | FN Test | 96T | 628.92 EUR |
Avian Influenza Virus Antigen Rapid Test Kit (Colloidal gold) |
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abx092015-40tests | Abbexa | 40 tests | 518.4 EUR |
Coronavirus (SARS-Cov-2) Antigen Rapid Test Device (Saliva) |
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IOV87952 | INVBIO | 20T/kit | 46.8 EUR |
Recombinant human Testin |
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P2531 | FN Test | 100ug | Ask for price |
Canine Parvovirus Antigen/Canine Coronavirus Antigen (CPV/CCV Ag) Rapid Test Kit |
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HG008 | EnoGene | 10 Tests/Kit | 21 EUR |
Human LY6G6F(Lymphocyte antigen 6 complex locus protein G6f) ELISA Kit |
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EH1837 | FN Test | 96T | 681.12 EUR |
Human PRAME(Melanoma antigen preferentially expressed in tumors) ELISA Kit |
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EH1290 | FN Test | 96T | 681.12 EUR |
Human TALLA-1(T-cell acute lymphoblastic leukemia antigen) ELISA Kit |
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EH3848 | FN Test | 96T | 681.12 EUR |
Mouse Testosterone ELISA Kit |
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EM1850 | FN Test | 96T | 628.92 EUR |
Human Testosterone ELISA Kit |
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EH4850 | FN Test | 96T | 628.92 EUR |
Mouse Cd74(HLA class II histocompatibility antigen gamma chain) ELISA Kit |
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EM6405 | FN Test | 96T | 681.12 EUR |
Human CD74(HLA class II histocompatibility antigen gamma chain) ELISA Kit |
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EH1531 | FN Test | 96T | 681.12 EUR |
Recombinant human Carcinoembryonic antigen-related cell adhesion molecule 16 |
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P2564 | FN Test | 100ug | Ask for price |
Newcastle Disease Virus Antigen Rapid Test Kit (Colloidal gold) |
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abx092016-40tests | Abbexa | 40 tests | 518.4 EUR |
Human SPOCK2(Testican-2) ELISA Kit |
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EH2271 | FN Test | 96T | 681.12 EUR |
Bovine T(Testosterone) ELISA Kit |
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EB0049 | FN Test | 96T | 681.12 EUR |
Recombinant human HLA class I histocompatibility antigen, A-1 alpha chain |
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P1957 | FN Test | 100ug | Ask for price |
Recombinant human HLA class II histocompatibility antigen, DQ beta 1 chain |
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P1966 | FN Test | 100ug | Ask for price |
Recombinant human Testican-2 |
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P1475 | FN Test | 100ug | Ask for price |
Human HLA-E(HLA class I histocompatibility antigen, alpha chain E) ELISA Kit |
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EH1817 | FN Test | 96T | 628.92 EUR |
Human F-TESTO(Free Testoterone) ELISA Kit |
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EH3092 | FN Test | 96T | 571.5 EUR |
Human TEX101(testis expressed 101) ELISA Kit |
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EH12903 | FN Test | 96T | 681.12 EUR |
Feline Panleukopenia Virus Antigen/Feline Herpesvirus Antigen (FPV/FHV) Rapid Test Kit |
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HG011 | EnoGene | 10 Tests/Kit | 17.5 EUR |
Human CEACAM1(Carcinoembryonic antigen-related cell adhesion molecule 1) ELISA Kit |
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EH0671 | FN Test | 96T | 681.12 EUR |
Human Chlamydia Trachomatis Antigen Rapid Test Kit (Colloidal gold) |
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abx092049-20tests | Abbexa | 20 tests | 276 EUR |
Mouse H2-Q7(H-2 class I histocompatibility antigen, Q7 alpha chain) ELISA Kit |
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EM0668 | FN Test | 96T | 681.12 EUR |
Human HLA-DRB5(HLA class II histocompatibility antigen, DR beta 5 chain) ELISA Kit |
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EH1734 | FN Test | 96T | 681.12 EUR |
Human HLA-B27(HLA class I histocompatibility antigen, B-27 alpha chain) ELISA Kit |
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EH1968 | FN Test | 96T | 628.92 EUR |
Human HLA-DQB2(HLA class II histocompatibility antigen, DQ beta 2 chain) ELISA Kit |
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EH9135 | FN Test | 96T | 681.12 EUR |
Mouse H2-Aa( H-2 class II histocompatibility antigen, A-B alpha chain) ELISA Kit |
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EM0643 | FN Test | 96T | 681.12 EUR |
Avian Influenza H5 Virus Antigen Rapid Test Kit (Colloidal gold) |
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abx092014-40tests | Abbexa | 40 tests | 585.6 EUR |
Avian Influenza H7 Virus Antigen Rapid Test Kit (Colloidal gold) |
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abx092017-40tests | Abbexa | 40 tests | 518.4 EUR |
Canine Distemper Virus Antigen/Canine Adenovirus Antigen (CDV/CAV Ag) Rapid Test Kit |
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HG009 | EnoGene | 10 Tests/Kit | 21 EUR |
SARS-CoV-2 and Influenza A+B Antigen Combo Rapid Test |
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ISIN-525H | Hangzhou AllTest Biotech | 25 Tests | 18.75 EUR |
Canine Distemper Virus Antigen/Canine Influenzavirus Antigen (CDV/CIV Ag) Rapid Test Kit |
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HG010 | EnoGene | 10 Tests/Kit | 21 EUR |
Recombinant human Testis-specific Y-encoded-like protein 5 |
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P1359 | FN Test | 100ug | Ask for price |
Canine Heartworm Antigen/Ehrlichia/Lyme Anaplasma Antibody Combo Test Card |
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C10791 | Ring Biotechnology Co | 10T | Ask for price |
Recombinant human Protein disulfide-isomerase-like protein of the testis |
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P2148 | FN Test | 100ug | Ask for price |
HBV-NRAg hepatitis B virus nucleic acid related antigen ELISA test |
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84 | Biobase | 96T/Box | Ask for price |
25 mm Test Tube Foam Rack |
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MIX1116 | Scientific Laboratory Supplies | EACH | 48 EUR |
COVID-19 RNA Test, 1 test/pack |
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U20250 | USTAR Biotechnologies (Hangzhou) | test | Ask for price |
Canine Parvovirus Antigen/Canine Distemper Virus Antigen /Canine Coronavirus Antigen (CPV/CDV/CCV Ag) Rapid Test Kit |
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HG027 | EnoGene | 10 Tests/Kit | 36.4 EUR |
Rat CA19-9(Carbohydrate antigen19-9) ELISA Kit |
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ER1907 | FN Test | 96T | 628.92 EUR |
HBsAg Test Card (Test in Whole Blood) |
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HBsAg-214 | Innovation Biotech | 4.0mm (strip in a card) 25cards/box | 0.2 EUR |
Human CA19-9(Carbohydrate antigen19-9) ELISA Kit |
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EH0363 | FN Test | 96T | 628.92 EUR |
HBsAg Test Strip (Test in Whole Blood) |
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HBsAg-213 | Innovation Biotech | 3.0mm (single pouch) 100pouches/box | 0.1 EUR |
Rat Pdha2(Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial) ELISA Kit |
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ER0417 | FN Test | 96T | 681.12 EUR |
Human PDHA2(Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial) ELISA Kit |
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EH1149 | FN Test | 96T | 681.12 EUR |
Feline Panleukopenia Virus Antigen/Feline Herpesvirus Antigen/Feline Calicivirus Antigen (FPV/FHV/FCV Ag) Rapid Test Kit |
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HG007 | EnoGene | 10 Tests/Kit | 38.5 EUR |
Canine Heartworm Antigen/Ehrlichia/Babesia Gibsoni/Anaplasma Antibody Combo Test Card |
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C10811 | Ring Biotechnology Co | 10T | Ask for price |
NOVATest IgG/IgM Antibody Rapid Test Kit (NOVA Test) |
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UNCOV-40 | Atlas Link Technology | 40 Tests | 115 EUR |
COD Test Kit 25 to 1500mg/L |
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WAT4314 | Scientific Laboratory Supplies | PK25 | 141 EUR |
Canine Parvo Virus Antigen (CPV Ag) Test Kit (Fluorescence Lateral Flow Immunoassay) |
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HG024 | EnoGene | 10 Tests/Kit | 28 EUR |
Test product |
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testttt | National Diagnostics | 0 | Ask for price |
Test Product |
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ZX001 | AAT Bioquest | 1mg | Ask for price |
Test Product |
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ZX002 | AAT Bioquest | 5mg | Ask for price |
Feline Plague Virus Antigen (FPV Ag) Test Kit (Fluorescence Lateral Flow Immunoassay) |
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HG021 | EnoGene | 10 Tests/Kit | 38.5 EUR |
Feline Herpes Virus Antigen (FHV Ag) Test Kit (Fluorescence Lateral Flow Immunoassay) |
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HG022 | EnoGene | 10 Tests/Kit | 59.5 EUR |
Feline Corona Virus Antigen (FCoV Ag) Test Kit (Fluorescence Lateral Flow Immunoassay) |
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HG023 | EnoGene | 10 Tests/Kit | 70 EUR |
Canine Corona Virus Antigen (CCV Ag) Test Kit (Fluorescence Lateral Flow Immunoassay) |
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HG026 | EnoGene | 10 Tests/Kit | 30.1 EUR |
Canine Distemper Virus Antigen (CDV Ag) Test Kit (Fluorescence Lateral Flow Immunoassay) |
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HG025 | EnoGene | 10 Tests/Kit | 31.5 EUR |
Mouse IL-25(Interleukin 25) ELISA Kit |
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EM1162 | FN Test | 96T | 628.92 EUR |
Mouse Hepc 25(Hepcidin 25) ELISA Kit |
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EM1601 | FN Test | 96T | 628.92 EUR |
Rat IL-25(Interleukin 25) ELISA Kit |
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ER1097 | FN Test | 96T | 628.92 EUR |
Rat Hepc 25(Hepcidin 25) ELISA Kit |
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ER1504 | FN Test | 96T | 571.5 EUR |
Recombinant human Forkhead box protein L1 |
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P1506 | FN Test | 100ug | Ask for price |
Recombinant human Forkhead box protein O4 |
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P1559 | FN Test | 100ug | Ask for price |
Recombinant human Forkhead box protein O6 |
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P1560 | FN Test | 100ug | Ask for price |
Recombinant human Forkhead box protein M1 |
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P1224 | FN Test | 100ug | Ask for price |
TESTO (Testosterone) ELISA test |
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19 | Biobase | 96T/Box | Ask for price |
Pregnancy Combo Test Card (Test in serum or urine) |
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INV-117 | Innovation Biotech | 4.0mm (strip in a card) 25cards/box | 0.15 EUR |
Human MMP-25(Matrix Metalloproteinase 25) ELISA Kit |
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EH3372 | FN Test | 96T | 628.92 EUR |
Chloride Test 70-1000 |
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WAT3613 | Scientific Laboratory Supplies | EACH | 140.4 EUR |
Pregnancy Combo Test Strip (Test in serum or urine) |
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INV-116 | Innovation Biotech | 3.0mm (single pouch) 100pouches/box | 0.05 EUR |
Feline Panleukopenia Virus Antigen/Feline Coronavirus Antigen/Feline Giardiasis Antigen (FeliD-3 Ag) Rapid Test Kit (FPV/FCoV/GIA Ag) |
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HG031 | EnoGene | 10 Tests/Kit | 17.5 EUR |
TB Test Card |
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INV-312 | Innovation Biotech | 4.0mm (strip in a card) 25cards/box | 0.46 EUR |
AFP Test Card |
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INV-1112 | Innovation Biotech | 4.0mm (strip in a card) 25cards/box | 0.44 EUR |
PSA Test Card |
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INV-1122 | Innovation Biotech | 4.0mm (strip in a card) 25cards/box | 0.52 EUR |
CEA Test Card |
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INV-1132 | Innovation Biotech | 4.0mm (strip in a card) 25cards/box | 0.52 EUR |
Overall test sensitivity was 84.9% (95% CI 79.1–89.4) and specificity was 99.5% (95% CI 98.7–99.8). Sensitivity increased to 95.8% (95% CI 90.5–98.2) for persons who sought care within 7 days of symptom onset. Test band intensity and time to result correlated strongly with viral load; thus, strong positive results could be read before the recommended time. Approximately 98% of all viable specimens with cycle threshold <30 were detected. Rapid antigen tests can detect symptomatic infections in the early phase of disease, thereby identifying the most infectious persons.